Retrograde Transport Pathway. (PDF) Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde transport, in which proteins and lipids are shuttled between endosomes and biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse range of cellular functions The anterograde pathway, from the endoplasmic reticulum through the trans-Golgi network to the cell surface, is utilized by trans-membrane and secretory proteins.The retrograde pathway, which directs traffic in the opposite direction, is used following endocytosis of exogenous molecules and recycling of membrane proteins.
(PDF) Retrograde transport pathways utilised by viruses and protein toxins from www.researchgate.net
In fact, the analysis of such toxins led to the discovery and description of retrograde transport pathways involved in endosome-to-Golgi transport (Olsnes and Pihl, 1972; Montanaro et al., 1973; Gonatas et al., 1975) Mechanistic studies that explore the molecular machinery involved in this retrograde trafficking route are shedding light on the functions of transport proteins and are providing fresh.
(PDF) Retrograde transport pathways utilised by viruses and protein toxins
In fact, the analysis of such toxins led to the discovery and description of retrograde transport pathways involved in endosome-to-Golgi transport (Olsnes and Pihl, 1972; Montanaro et al., 1973; Gonatas et al., 1975) In fact, the analysis of such toxins led to the discovery and description of retrograde transport pathways involved in endosome-to-Golgi transport (Olsnes and Pihl, 1972; Montanaro et al., 1973; Gonatas et al., 1975) Retrograde transport of growth-inhibitory signals may be part of the normal neuronal maturation pathway during development
Death by Retrograde Transport Avoiding the Apoptosis Default Cell. Retrograde transport of growth-inhibitory signals may be part of the normal neuronal maturation pathway during development Initially, it was considered that mammalian retromer functions in the equivalent retrograde transport pathway, as demonstrated by retromer dependency of retrograde transport of cation-independent.
Generalised simplified retrograde routes available to ER trafficking. Retrograde transport, in which proteins and lipids are shuttled between endosomes and biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse range of cellular functions The retrograde transport of membrane proteins from endosomes to the trans-Golgi network (TGN) is essential for internalization and recycling of membrane proteins which control a variety of physiological processes including (i) lysosomal biogenesis, (ii) ion and glucose transport, (iii) processing and secretion of polypeptide precursors and (iv) secretion of signaling proteins that regulate.